N. Schueller
Papers
1
Total Citations
131
H-Index
1
About
N. Schueller is a leading figure in structural biology, best known for pioneering high-throughput protein crystallization methods. Their most impactful work, "A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results" (2003, 131 citations), revolutionized the field by demonstrating the practical, day-to-day success of a robotic system for 100-nanoliter-scale vapour-diffusion sitting-drop experiments. This landmark study surveyed results from over 50 unrelated protein samples, providing a critical snapshot of crystallization trials and validating that miniaturization could dramatically accelerate structural determination. By proving that nanolitre-scale setups reliably yield diffraction-quality crystals, Schueller's contributions enabled laboratories worldwide to screen thousands of conditions with minimal protein consumption, significantly reducing the bottleneck in X-ray crystallography. Their work has become a foundational reference for automation in structural genomics, directly influencing the design of modern crystallization robots and high-throughput pipelines. Schueller's achievements continue to empower researchers to tackle increasingly challenging macromolecular targets, making them a pivotal figure in the evolution of structural biology.
Research Focus
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Top Papers
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