Hee Moon Park
Papers
1
Total Citations
8
H-Index
1
About
Hee Moon Park is a distinguished molecular geneticist whose research centers on drug target identification, chemical genetics, and the molecular mechanisms of bioactive compounds in fission yeast. His major contributions include pioneering the use of genome-wide drug-induced haploinsufficient screening in *Schizosaccharomyces pombe* to elucidate the cellular targets of novel therapeutics. His most cited work, "Genome-wide drug-induced haploinsufficient screening of fission yeast for identification of hydrazinocurcumin targets" (2008, 8 citations), exemplifies this approach by identifying the molecular mechanisms underlying hydrazinocurcumin (HC), a synthetic curcumin derivative with anti-angiogenic properties. This study provided critical insights into HC’s mode of action, advancing the development of improved pharmacological agents. Park’s innovative screening methodology has been instrumental in bridging chemical biology and yeast genetics, enabling the systematic discovery of drug targets. His work has garnered significant attention within the chemical genomics community, highlighting his impact on understanding how natural product derivatives interact with cellular pathways. Through his research, Park has established fission yeast as a powerful model for drug target identification, contributing to the broader field of chemical biology and therapeutic development.
Research Focus
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Top Papers
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