Seung Tae Baek
Papers
1
Total Citations
8
H-Index
1
About
Seung Tae Baek is a molecular biologist whose research centers on the mechanisms of drug action and cellular stress responses, with a particular focus on the fission yeast model system. His most cited work, a 2008 genome-wide drug-induced haploinsufficiency screen in fission yeast, identified the molecular targets of hydrazinocurcumin (HC)—a synthetic curcumin derivative known to inhibit angiogenesis. By systematically mapping the genetic interactions that confer drug sensitivity, Baek’s study provided critical insights into HC’s previously unknown mechanisms of action, laying the groundwork for developing improved anti-angiogenic compounds with better pharmacological properties. This foundational research, cited 8 times, exemplifies his approach of combining chemical genetics with functional genomics to unravel complex drug-target networks. Baek’s contributions are particularly valuable for researchers interested in drug discovery, chemical biology, and the use of yeast as a platform for high-throughput screening. His work underscores the power of model organisms in translating chemical biology findings into potential therapeutic strategies.
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Top Papers
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