Yannis L. Loukas
Papers
12
Total Citations
333
H-Index
11
About
Yannis L. Loukas is a prominent analytical and pharmaceutical scientist whose research has made substantial contributions to the field of bioanalytical method development, particularly in the quantification of drugs and their metabolites in human biological matrices. His work centers on the development and validation of high-throughput liquid chromatography/tandem mass spectrometry (LC-MS/MS) methods, with a consistent emphasis on automation, precision, and clinical applicability. Loukas has pioneered the use of 96-well format plate-based liquid-liquid extraction systems to streamline sample preparation workflows, dramatically improving efficiency in bioequivalence studies. His validated methods span a diverse range of therapeutically important compounds, including the antibiotic colistin (57 citations), the Alzheimer's drug donepezil (46 citations), antifungals such as itraconazole and terbinafine, the cardiovascular agent simvastatin, and the antipsychotic risperidone. This breadth underscores his versatility across multiple pharmacological classes. Beyond method development, Loukas has contributed to pharmacogenomics research, notably examining how CYP2C19 polymorphisms influence omeprazole pharmacokinetics. With a body of work accumulating hundreds of citations, his research continues to serve as a methodological foundation for clinical pharmacokinetics and drug development laboratories worldwide.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 9
- 10