Catherine K. Markopoulou
Papers
1
Total Citations
57
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1
About
Catherine K. Markopoulou is a leading figure in bioanalytical chemistry, with her research centered on the development and validation of advanced liquid chromatography-tandem mass spectrometry (LC-MS/MS) methodologies for therapeutic drug monitoring. Her most impactful contribution is the creation of a fully automated, high-throughput LC-MS/MS method for quantifying colistin A and B in human plasma, a critical advance for optimizing the dosing of this last-resort antibiotic. This work, published in 2010 and cited 57 times, revolutionized sample preparation by employing robotic handling and 2.2 mL 96-deep-well plates, dramatically increasing efficiency and reproducibility. Markopoulou’s innovations have directly enhanced the clinical management of multidrug-resistant infections, enabling precise pharmacokinetic studies and safer patient outcomes. Her dedication to automation and method robustness has set new standards in bioanalysis, making her a key contributor to the field’s evolution toward faster, more reliable drug quantification.
Research Focus
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