Yannis Dotsikas
Papers
13
Total Citations
453
H-Index
11
About
Yannis Dotsikas is a pharmaceutical scientist whose research sits at the intersection of analytical chemistry, bioanalysis, and pharmacokinetics. He is best known for pioneering and advancing high-throughput automated methods for quantifying drugs and their metabolites in biological matrices, particularly human plasma and urine. His most cited work, a 2018 review on robotic automation of solvent extraction for bioanalysis (120 citations), positions him as a leading authority on modernizing pharmaceutical sample preparation workflows. Throughout his career, Dotsikas has developed and rigorously validated LC-MS/MS methods for a diverse range of clinically important drugs — including colistin, donepezil, itraconazole, simvastatin, risperidone, terbinafine, and anastrozole — consistently leveraging 96-well plate formats and robotic automation to achieve efficiency and reproducibility at scale. These contributions have been instrumental in supporting bioequivalence studies and therapeutic drug monitoring. His 2016 investigation into CYP2C19 polymorphisms and omeprazole pharmacokinetics further demonstrates his interest in bridging analytical method development with personalized medicine. With a body of work accumulating over 400 citations, Dotsikas has made enduring contributions to the standardization and modernization of bioanalytical science.
Research Focus
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