Stefanos Soumelas
Papers
1
Total Citations
11
H-Index
1
About
Stefanos Soumelas is a distinguished bioanalytical chemist whose work centers on the development and validation of high-throughput, automated methods for quantifying pharmaceutical compounds in biological matrices. His major contributions lie in advancing liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques, significantly improving the efficiency and reliability of therapeutic drug monitoring. Soumelas’s most cited paper, “Validation of a Novel, Fully Automated High Throughput High-Performance Liquid Chromatographic/Tandem Mass Spectrometric Method for Quantification of Pantoprazole in Human Plasma” (2010, 11 citations), exemplifies his impact. In this work, he pioneered a streamlined protocol requiring only 100 µL of plasma, employing liquid-liquid extraction in 96-well plates to simultaneously extract pantoprazole and its internal standard, omeprazole. This innovation drastically reduced sample preparation time and solvent use while maintaining exceptional sensitivity and reproducibility. By automating a traditionally manual process, Soumelas enabled faster, more cost-effective clinical and pharmacokinetic analyses. His research is particularly valuable for students and researchers seeking to optimize bioanalytical workflows, demonstrating how method miniaturization and automation can enhance throughput without compromising data quality.
Research Focus
Key Achievements
Top Papers
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