Filomila Kolocouri
Papers
3
Total Citations
57
H-Index
3
About
Filomila Kolocouri is a specialist in bioanalytical chemistry, with a research focus on the development and validation of advanced liquid chromatography-tandem mass spectrometry (LC–MS/MS) methods for quantifying pharmaceutical compounds in human plasma. Her work sits at the intersection of analytical method development, pharmacokinetics, and bioequivalence testing, addressing critical needs in clinical and drug development research. Kolocouri's most cited contribution — an improved LC–MS/MS method for the simultaneous quantification of simvastatin and simvastatin acid in human plasma (2007, 42 citations) — demonstrated her ability to produce rigorously validated analytical tools for widely prescribed cardiovascular drugs. Her subsequent research pushed the boundaries of throughput and efficiency, pioneering fully automated high-throughput platforms using 96 deep-well plate formats and robotic liquid handling systems. These innovations, applied to drugs such as pantoprazole and the ACE inhibitor cilazapril, significantly reduced manual processing time while maintaining analytical precision — a meaningful advancement for laboratories conducting large-scale bioequivalence studies. Through her body of work, Kolocouri has made a practical and lasting contribution to the standardization and automation of plasma sample preparation, offering valuable methodological frameworks that continue to inform bioanalytical practice in pharmaceutical research.
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