Papers
1
Total Citations
6
H-Index
1
About
Wensheng Yu is a leading researcher in HIV eradication and pharmacokinetic/pharmacodynamic (PK/PD) modeling, with a focus on developing novel strategies to eliminate latent HIV reservoirs. Their most-cited work, "In Vitro Pharmacokinetic/Pharmacodynamic Modeling of HIV Latency Reversal by Novel HDAC Inhibitors Using an Automated Platform" (2021, 6 citations), introduces an innovative automated platform to evaluate histone deacetylase inhibitors (HDACis) for reversing HIV latency—a critical barrier to curing chronic infection. By integrating in vitro PK/PD modeling, Yu’s research provides a high-throughput, quantitative framework to assess drug efficacy, accelerating the identification of latency-reversing agents that could complement antiretroviral therapy. This work bridges pharmacology and virology, offering a reproducible method to optimize dosing and combination strategies. Yu’s contributions are pivotal in the fight against HIV persistence, demonstrating how precision modeling can advance translational research toward a functional cure. Their automated platform represents a notable achievement, enabling more efficient screening of HDACis and highlighting Yu’s role in shaping next-generation HIV eradication approaches.
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Top Papers
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