In vitro

Robotic fluidic coupling and interrogation of multiple vascularized organ chips

Richard Novák, Susan Marquez, Debarun Das, Aaron Delahanty, Anna Herland, Ben M. Maoz, Sauveur S. F. Jeanty, Mahadevabharath R. Somayaji, Morgan A. Burt, Elizabeth Calamari, Angeliki Chalkiadaki, Alexander Cho, Youngjae Choe, David B. Chou, Michael J. Cronce, Stephanie Dauth, Toni Divic, Jose Fernandez-Alcon, Thomas C. Ferrante, John P. Ferrier, Edward A. Fitzgerald, Rachel C. Fleming, Sasan Jalili‐Firoozinezhad, Thomas Grevesse, Josue A. Goss, Tiama Hamkins-Indik, Olivier Henry, Chris Hinojosa, Tessa Huffstater, Kyung‐Jin Jang, Ville Kujala, Lian Leng, Robert Mannix, Yuka Milton, Janna Nawroth, Bret Nestor, Carlos F. Ng, Blakely B. O’Connor, Tae‐Eun Park, Henry Sanchez, Josiah Sliz, Alexandra Sontheimer-Phelps, Ben Swenor, Guy Thompson, George J. Touloumes, Zachary Tranchemontagne, Norman Wen, Moran Yadid, Anthony Bahinski, Geraldine A. Hamilton, Daniel Levner, Oren Levy, Andrzej Przekwas, Rachelle Prantil‐Baun, Kevin Kit Parker, Donald E. Ingber

Citations: 401 • 2020

A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions

P.-C. Klöhn, Lars Stoltze, Eckhard Flechsig, Masato Enari, Charles Weissmann

Citations: 326 • 2003

Selective killing of ovarian cancer cells through induction of apoptosis by nonequilibrium atmospheric pressure plasma

Sachiko Iseki, Kae Nakamura, Moemi Hayashi, Hiromasa Tanaka, Hiroki Kondo, Hiroaki Kajiyama, Hiroyuki Kano, Fumitaka Kikkawa, Masaru Hori

Citations: 314 • 2012

BIRB796 Inhibits All p38 MAPK Isoforms in Vitro and in Vivo

Yvonne Kuma, Guadalupe Sabio, Jenny Bain, Natalia Shpiro, Rodolfo Márquez, Ana Cuenda

Citations: 310 • 2005

Scaffold-Free Tubular Tissues Created by a Bio-3D Printer Undergo Remodeling and Endothelialization when Implanted in Rat Aortae

M. Itoh, Koichi Nakayama, Ryo Noguchi, Keiji Kamohara, K Furukawa, Kazuyoshi Uchihashi, Shuji Toda, Jun‐ichi Oyama, Koichi Node, Shigeki Morita

Citations: 295 • 2015

<i>In vivo</i> bioprinting for computer- and robotic-assisted medical intervention: preliminary study in mice

Virginie Kériquel, Fabien Guillemot, Isabelle Arnault, Bertrand Guillotin, Sylvain Miraux, Joëlle Amédée, Jean‐Christophe Fricain, Sylvain Catros

Citations: 275 • 2010

The fluorometric microculture cytotoxicity assay

Elin Lindhagen, Peter Nygren, Rolf Larsson

Citations: 236 • 2008

Primary cultures of brain microvessel endothelial cells: a valid and flexible model to study drug transport through the blood–brain barrier in vitro

Helmut Franke, Hans‐Joachim Galla, Carsten T. Beuckmann

Citations: 228 • 2000

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model

Terence I. Moy, Annie L. Conery, Jonah Larkins‐Ford, Gang Wu, Ralph Mazitschek, Gabriele Casadei, Kim Lewis, Anne E. Carpenter, Frederick M. Ausubel

Citations: 210 • 2009

An improved method for the in vitro evolution of aptamers and applications in protein detection and purification

Michael Murphy

Citations: 202 • 2003

3D printing facilitated scaffold-free tissue unit fabrication

Yu Jun Tan, Dylan Richards, Thomas C. Trusk, Richard P. Visconti, Michael J. Yost, Mark S. Kindy, Christopher J. Drake, W. Scott Argraves, Roger R. Markwald, Ying Mei

Citations: 149 • 2014

Optimization of a Higher Throughput Microsomal Stability Screening Assay for Profiling Drug Discovery Candidates

Li Di, Edward H. Kerns, Yan Hong, Teresa Kleintop, Oliver J. McConnell, Donna M. Huryn

Citations: 137 • 2003

Development of an in vitro cytotoxicity model for aerosol exposure using 3D reconstructed human airway tissue; application for assessment of e-cigarette aerosol

Louise Neilson, Courtney Mankus, David Thorne, George R. Jackson, Jason DeBay, Clive Meredith

Citations: 134 • 2015

Biomechanical consequences of PCL deficiency in the knee under simulated muscle loads—an in vitro experimental study

Guoan Li, Louis E. DeFrate, Shay Zayontz, Vaida Glatt, Bertram Zarins

Citations: 129 • 2002

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis

Steffan Vartanian, P. Taylur, James Lee, Peter M. Haverty, Donald S. Kirkpatrick, Kebing Yu, David Stokoe

Citations: 114 • 2015

Effect of copper-doped silicate 13–93 bioactive glass scaffolds on the response of MC3T3-E1 cells in vitro and on bone regeneration and angiogenesis in rat calvarial defects in vivo

Yinan Lin, Wei Xiao, B. Sonny Bal, Mohamed N. Rahaman

Citations: 110 • 2016

In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed

Flavio Bonanini, Dorota Kurek, Sara Previdi, Arnaud Nicolas, Delilah Hendriks, Sander Ruiter, Marine Meyer, Maria Clapés Cabrer, Roelof Dinkelberg, Silvia Bonilla García, Bart Kramer, Thomas Olivier, Huili Hu, Carmen López‐Iglesias, Frederik Schavemaker, Erik Walinga, Devanjali Dutta, Karla Queiroz, Karel Domanský, Bob Ronden, Jos Joore, Henriëtte L. Lanz, Peter J. Peters, Sebastiaan J. Trietsch, Hans Clevers, Paul Vulto

Citations: 108 • 2022

High Throughput Screening of Physicochemical Properties and In Vitro ADME Profiling in Drug Discovery

Hong Wan, Anders Holmén

Citations: 97 • 2009

High Throughput, Polymeric Aqueous Two‐Phase Printing of Tumor Spheroids

Ehsan Atefi, Stephanie Lemmo, Darcy Fyffe, Gary D. Luker, Hossein Tavana

Citations: 93 • 2014

A Repurposing Strategy Identifies Novel Synergistic Inhibitors of <i>Plasmodium falciparum</i> Heat Shock Protein 90

Dea Shahinas, Michael N. Liang, Alessandro Datti, Dylan R. Pillai

Citations: 90 • 2010