William Newhard
Papers
2
Total Citations
12
H-Index
2
About
William Newhard is a researcher at the forefront of infectious disease pharmacology, with a primary focus on HIV latency reversal and antibacterial pharmacodynamics. His work addresses two critical challenges: eradicating persistent HIV reservoirs and streamlining the evaluation of antibiotic efficacy. Newhard’s major contributions include the development of an automated platform for *in vitro* pharmacokinetic/pharmacodynamic (PK/PD) modeling of HIV latency reversal, specifically testing novel histone deacetylase inhibitors (HDACis). This work, cited 6 times, provides a high-throughput method to identify compounds that can “shock and kill” latent HIV, a key barrier to a cure. Additionally, he pioneered a fully automated agar-based system for measuring viable bacterial growth, also with 6 citations, which significantly reduces manual labor in dynamic antibacterial studies. This innovation enables more efficient dosing strategy assessments before moving to *in vivo* models. By integrating automation into complex PK/PD analyses, Newhard is accelerating the discovery of effective therapies for both HIV and bacterial infections, making his work highly relevant to translational pharmacology and infectious disease research.
Research Focus
Key Achievements
Top Papers
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