Jason Cassaday
Papers
5
Total Citations
79
H-Index
5
About
Jason Cassaday is a pharmacologist and laboratory automation specialist whose career bridges drug discovery, high-throughput screening, and preclinical pharmacology. His foundational work in the early 2000s focused on developing cutting-edge assay systems for identifying drug candidates targeting G protein-coupled receptors (GPCRs) and metabotropic glutamate receptors — critical proteins implicated in numerous therapeutic areas. His 2003 paper on automated screening of metabotropic glutamate receptor antagonists (39 citations) and his 2008 development of an ultra-high-throughput 1,536-well GTPγS scintillation proximity assay (22 citations) demonstrated his expertise in scaling and automating complex biochemical screens to accelerate drug discovery pipelines. Cassaday has since expanded his focus toward infectious disease, contributing innovative automated platforms for studying HIV latency reversal using HDAC inhibitors and quantifying antibacterial activity through agar-based growth measurement systems. His 2016 work on automated cross-titration experiments further underscores his commitment to streamlining compound optimization workflows. Across his career, Cassaday's defining contribution is the intelligent application of laboratory automation to solve complex pharmacological and pharmacokinetic challenges, making sophisticated experimental approaches more efficient, reproducible, and accessible for researchers worldwide.
Research Focus
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