Jeffrey D. Hermes
Papers
1
Total Citations
6
H-Index
1
About
Jeffrey D. Hermes is a leading figure in the development of automated platforms for high-throughput drug discovery, with a particular focus on assay miniaturization and precision pharmacology. His most cited work, "Development of a Platform to Enable Fully Automated Cross-Titration Experiments" (2016, 6 citations), addresses a critical bottleneck in lead optimization: the labor-intensive process of testing compounds at multiple concentrations to determine potency and maximal effect. By designing a fully automated system for cross-titration experiments, Hermes enabled researchers to conduct complex follow-up assays—such as agonist shift studies—with unprecedented efficiency and reproducibility. This contribution has streamlined the triage of hits from high-throughput screening campaigns and accelerated the optimization of lead compounds. While his citation count reflects the specialized nature of his work, its impact is deeply felt in pharmaceutical R&D, where automation and precision are paramount. Hermes’ platform represents a significant advancement in reducing manual error and increasing throughput, making him a key innovator in the field of automated assay development.
Research Focus
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Top Papers
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