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About

Raimond B. G. Ravelli is a leading figure in macromolecular crystallography, with a career dedicated to advancing the tools and techniques that enable high-throughput structural biology. His research focuses on the automation and optimization of X-ray data collection at synchrotron beamlines, directly addressing the practical challenges faced by structural biologists. Ravelli’s most impactful contribution is the development of the SPINE standard sample holder, a modified cryocooled vial and mount system designed for robotic sample changers. This innovation, detailed in his 2006 paper (111 citations), has become a de facto standard across synchrotrons worldwide, dramatically increasing the efficiency and reproducibility of macromolecular crystallography experiments. He further advanced the field by defining best practices for data collection using next-generation beamline instruments, as outlined in his 2007 work (16 citations), which guides researchers in maximizing data quality from small, intense X-ray beams. Through these achievements, Ravelli has not only streamlined the sample mounting process but also empowered the global structural biology community to solve complex biological structures faster and with greater accuracy.