Daniel Holzinger

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About

Daniel Holzinger is a pioneering oral and maxillofacial surgeon whose research centers on the development and clinical translation of robotic laser osteotomy, particularly for complex craniomaxillofacial procedures. His major contribution is the introduction of the Cold Ablation Robot-Guided Laser Osteotome (CARLO®), a compact, stand-alone device that overcomes the geometric and physical limitations of conventional rotating and piezosurgery instruments. By integrating multiple sensory, steering, and safety elements, CARLO enables precise, contact-free bone cutting, translating digital surgical planning directly to the operating room. Holzinger’s landmark 2021 study, cited 31 times, reported the first-in-human application of this technology in 14 consecutive patients requiring midface osteotomies for orthognathic surgery, demonstrating clinical feasibility. A subsequent 2024 multicenter evaluation in 28 patients, cited 5 times, confirmed the device’s performance and safety for linear midface cuts. These works collectively establish a new paradigm in bone surgery, reducing mechanical trauma and enhancing precision. Holzinger’s research bridges engineering and surgery, offering a transformative tool for maxillofacial reconstruction and setting the stage for broader adoption of robotic laser systems in orthopedics and neurosurgery.