G. Millesi

Papers

Total Citations

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About

G. Millesi is a pioneering surgeon and researcher at the forefront of computer-assisted and robotic maxillofacial surgery. His primary research focus is the development and clinical translation of advanced osteotomy technologies, specifically the Cold Ablation Robot-Guided Laser Osteotome (CARLO®). Millesi’s major contribution is the successful transition of this innovative robotic laser system from the laboratory bench to the operating room. He led the first-in-human application of CARLO® for midface osteotomies, demonstrating its clinical feasibility and safety. His work addresses the limitations of conventional mechanical bone-cutting tools by enabling precise, contact-free, and geometrically superior bone cuts, directly translating digital surgical plans into the operative field. The impact of this translational work is evident in his most-cited publications, including the landmark 2021 study (31 citations) reporting on 14 consecutive patients and a subsequent 2024 multi-center evaluation of 28 cases. By proving the system’s performance and safety, Millesi has established a new paradigm for osteotomy surgery, paving the way for broader adoption of robotic laser technology in craniomaxillofacial procedures.