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About

Winnie Brehmer is a leading figure in structural biology, specializing in the development of high-throughput methods for macromolecular crystallography. Her major contributions center on overcoming the challenges of working with small, radiation-sensitive crystals, particularly at microfocus synchrotron and X-ray free-electron laser (XFEL) facilities. Brehmer is best known for pioneering high-density sample grids, which enable the efficient mounting and data collection from multiple crystals in a single experiment—a technique that has garnered over 75 citations for its impact on productivity. Her work is critical for advancing femtosecond crystallography, where rapid, efficient sample delivery is essential. By streamlining data collection from challenging samples, Brehmer’s innovations have accelerated structural studies of proteins that were previously intractable, directly supporting breakthroughs in drug discovery and fundamental biology. Her achievements reflect a dedication to enabling the broader scientific community to tackle complex structural problems with greater speed and reliability.