Stefan Fiedler

Papers

Total Citations

840

H-Index

About

Stefan Fiedler is a leading figure in structural biology, renowned for his instrumental role in designing and operating cutting-edge synchrotron beamlines at the PETRA III facility (DESY, Hamburg). His research centers on developing advanced X-ray scattering and crystallography instrumentation to solve macromolecular structures. Fiedler’s major contributions include the creation of the P12 beamline, a high-brilliance facility dedicated to biological small-angle X-ray scattering (SAXS). As detailed in his highly cited 2015 paper (611 citations), P12 features versatile sample environments and automation, enabling high-throughput, low-background solution scattering experiments that are critical for studying dynamic biological complexes. He also co-developed the P13 macromolecular crystallography beamline (229 citations), which supports tunable, low-energy phasing for challenging crystal structures. These facilities have become essential resources for the global structural biology community, collectively driving thousands of studies. Fiedler’s work exemplifies the profound impact of beamline engineering on biological discovery, empowering researchers to visualize everything from flexible proteins to large assemblies with unprecedented precision and efficiency.