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About

Daniel Franke is a prominent researcher in biological small-angle X-ray scattering (SAXS), with particular expertise in synchrotron instrumentation, automation, and high-throughput structural biology methods. Based primarily at EMBL Hamburg, Franke has played a central role in advancing the infrastructure that enables modern solution scattering experiments on biological macromolecules. His most influential contribution — a 2015 paper describing the versatile sample environments at the P12 beamline at PETRA III (DESY, Hamburg), now cited over 610 times — established a gold-standard facility for BioSAXS research worldwide. His earlier work on automated sample-changing robotics, dating back to 2008, helped pioneer the high-throughput approaches that have become indispensable to the field. Alongside colleagues, he has developed integrated systems for automated data acquisition and analysis, dramatically lowering the barrier to large-scale structural studies and enabling researchers globally to characterize proteins and other macromolecules in solution with unprecedented efficiency. With a body of work accumulating over 1,100 citations, Franke's technical innovations have quietly underpinned a generation of structural biology discoveries, making him an essential figure in synchrotron-based biophysical research.