Papers
4
Total Citations
980
H-Index
4
About
Manuel Mayr is a pioneering cardiovascular researcher whose work has fundamentally reshaped our understanding of vascular disease through the lens of proteomics and lipidomics. His research focuses on the extracellular matrix (ECM) of the vasculature, atherosclerotic plaque composition, and the role of microparticles in inflammation. Mayr’s landmark studies include the first comprehensive proteomic characterization of the human aortic ECM (290 citations) and a detailed analysis of ECM remodeling in abdominal aortic aneurysms (286 citations), revealing previously unknown protein changes driving aneurysm progression. He also developed innovative mass spectrometry approaches to profile lipids in atherosclerotic plaques (210 citations), providing new insights into plaque vulnerability. Notably, his work on neutrophil microparticles (194 citations) uncovered their functional heterogeneity and distinct proteomes, linking them to vascular inflammation. Mayr’s contributions have established foundational knowledge of vascular ECM biology and advanced the use of proteomics in cardiovascular research, making him a leading figure in the field.
Research Focus
Key Achievements
Top Papers
- 1Proteomics Characterization of Extracellular Space Components in the Human Aorta290 citations · 2010
- 2
- 3Comparative Lipidomics Profiling of Human Atherosclerotic Plaques210 citations · 2011
- 4