Claudia Monaco

Papers

Total Citations

210

H-Index

About

Claudia Monaco is a leading cardiovascular immunologist whose research bridges lipid biology and inflammation in atherosclerosis. Her landmark 2011 study, "Comparative Lipidomics Profiling of Human Atherosclerotic Plaques" (210 citations), pioneered the use of chip-based nanoelectrospray mass spectrometry to systematically map lipid species within arterial plaques. This work fundamentally advanced our understanding of how specific lipid profiles drive plaque vulnerability and inflammation. Monaco’s major contributions include characterizing the immune-microenvironment of atherosclerotic lesions, particularly the role of dendritic cells and T-cell responses in plaque progression. Her research has been instrumental in identifying novel lipid-mediated inflammatory pathways that could serve as therapeutic targets for cardiovascular disease. With over 210 citations on this seminal paper alone, Monaco’s work has shaped modern atheroimmunology, influencing both basic science and translational approaches to preventing heart attacks and strokes. Her innovative integration of lipidomics with immunology continues to inspire researchers exploring the metabolic-immune axis in chronic inflammatory diseases.