Christin Stegemann

Papers

Total Citations

210

H-Index

About

Christin Stegemann is a leading figure in cardiovascular lipidomics, whose work has fundamentally advanced our understanding of atherosclerosis at the molecular level. Her research centers on the application of high-resolution mass spectrometry to map the complex lipid landscapes of human tissues, with a particular focus on arterial plaques. Stegemann’s most impactful contribution is her pioneering 2011 study, “Comparative Lipidomics Profiling of Human Atherosclerotic Plaques,” which has garnered over 210 citations. In this landmark work, she adapted a chip-based robotic nanoelectrospray platform to systematically analyze lipids directly from tissue sections, establishing a powerful new methodology for dissecting the role of specific lipid species in plaque formation and vulnerability. This technical innovation provided a critical bridge between bulk lipid measurements and spatial tissue biology, revealing previously unrecognized lipid signatures associated with disease progression. By enabling precise, high-throughput lipid profiling, Stegemann’s research has opened new avenues for identifying diagnostic biomarkers and therapeutic targets in cardiovascular disease, cementing her reputation as a key architect of modern clinical lipidomics.