Bioinformatics

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

Jesse W.-H. Li, John C. Vederas

Citations: 2051 • 2009

Lab-on-a-chip: microfluidics in drug discovery

Petra S. Dittrich, A. Manz

Citations: 1828 • 2006

Micro/nanorobots for biomedicine: Delivery, surgery, sensing, and detoxification

Jinxing Li, Berta Esteban‐Fernández de Ávila, Wei Gao, Liangfang Zhang, Joseph Wang

Citations: 1503 • 2017

Core microbiomes for sustainable agroecosystems

Hirokazu Toju, Kabir Peay, Masato Yamamichi, Kazuhiko Narisawa, Kei Hiruma, Ken Naito, Shinji Fukuda, Masayuki Ushio, Shinji Nakaoka, Yusuke Onoda, Kentaro Yoshida, Klaus Schlaeppi, Yang Bai, Ryo Sugiura, Yasunori Ichihashi, Kiwamu Minamisawa, E. Toby Kiers

Citations: 1035 • 2018

Tumour-targeting bacteria engineered to fight cancer

Shibin Zhou, Claudia Gravekamp, David Bermudes, Ke Liu

Citations: 792 • 2018

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

Pasi Soininen, Antti J. Kangas, Peter Würtz, Taru Tukiainen, Tuulia Tynkkynen, Reino Laatikainen, Marjo‐Riitta Järvelin, Mika Kähönen, Terho Lehtimäki, Jorma Viikari, Olli T. Raitakari, Markku J. Savolainen, Mika Ala‐Korpela

Citations: 641 • 2009

Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics

Rak-Hwan Kim, Dae‐Hyeong Kim, Jianliang Xiao, Bong Hoon Kim, Sang-Il Park, Bruce Panilaitis, Roozbeh Ghaffari, Jimin Yao, Ming Li, Zhuangjian Liu, Viktor Malyarchuk, Dae Gon Kim, An‐Phong Le, Ralph G. Nuzzo, David L. Kaplan, Fiorenzo G. Omenetto, Yonggang Huang, Zhan Kang, John A. Rogers

Citations: 639 • 2010

Advancing Drug Discovery via Artificial Intelligence

H. C. Stephen Chan, Hanbin Shan, Thamani Dahoun, Horst Vogel, Shuguang Yuan

Citations: 634 • 2019

Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data

Alexander Aliper, Sergey Plis, Artem V. Artemov, Alvaro Ulloa, Polina Mamoshina, Alex Zhavoronkov

Citations: 600 • 2016

Analyzing proteome topology and function by automated multidimensional fluorescence microscopy

Walter Schubert, Bernd Bonnekoh, Ansgar J. Pommer, Lars Philipsen, Raik Böckelmann, Yanina N. Malykh, Harald Gollnick, Manuela Friedenberger, Marcus Bode, Andreas Dress

Citations: 495 • 2006

Plant natural products: Back to the future or into extinction?

James D. McChesney, Sylesh K. Venkataraman, John T. Henri

Citations: 376 • 2007

Recent developments in magnetically driven micro- and nanorobots

Xiangzhong Chen, Marcus Hoop, Fajer Mushtaq, Erdem Siringil, Chengzhi Hu, Bradley J. Nelson, Salvador Pané

Citations: 372 • 2017

Keynote review: Structural biology and drug discovery

Miles Congreve, Christopher W. Murray, Tom L. Blundell

Citations: 340 • 2005

High-Throughput Microarray-Based Enzyme-Linked Immunosorbent Assay (ELISA)

Leo G Mendoza, P. McQuary, Ann Mongan, R. Gangadharan, S. Brignac, M. Eggers

Citations: 328 • 1999

The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis

Dwaine F. Emerich, Christopher G. Thanos

Citations: 309 • 2006

Innovative tools for detection of plant pathogenic viruses and bacteria

Marı́a M. López, Edson Bertolini, Antonio Olmos, P. Caruso, M.T. Gorris, P. Llop, Ramón Penyalver, M. Cambra

Citations: 309 • 2003

Automated sample preparation with SP3 for low‐input clinical proteomics

Torsten Müller, Mathias Kalxdorf, Rémi Longuespée, Daniel Kazdal, Albrecht Stenzinger, Jeroen Krijgsveld

Citations: 295 • 2020

A Fully Automated Robotic System for Microinjection of Zebrafish Embryos

Wenhui Wang, Xinyu Liu, Danielle Gélinas, Brian Ciruna, Yu Sun

Citations: 272 • 2007

Artificial Intelligence in Colorectal Cancer Screening, Diagnosis and Treatment. A New Era

Athanasia Mitsala, Christos Tsalikidis, Μichail Pitiakoudis, Constantinos Simopoulos, Alexandra Tsaroucha

Citations: 264 • 2021

Interventions to reduce social isolation and loneliness during COVID-19 physical distancing measures: A rapid systematic review

Christopher Y. K. Williams, A Townson, Milan Kapur, Alice F. Ferreira, Rebecca Nunn, Julieta Galante, Veronica Phillips, Sarah Gentry, Juliet A. Usher‐Smith

Citations: 259 • 2021