Qingbo Xu

King's College London, Norwich University

Papers

Total Citations

496

H-Index

About

Qingbo Xu is a pioneering cardiovascular researcher whose work has fundamentally advanced our understanding of vascular disease mechanisms. His primary research areas encompass extracellular matrix remodeling in aortic aneurysms and lipid metabolism in atherosclerosis. In his landmark 2011 study on abdominal aortic aneurysms (286 citations), Xu employed cutting-edge proteomics to reveal that pathological ECM remodeling extends far beyond the well-known elastolysis and collagenolysis, identifying widespread changes in multiple matrix proteins that reshape our understanding of aneurysm pathogenesis. His equally influential work on atherosclerotic plaques (210 citations) pioneered the use of chip-based nanoelectrospray mass spectrometry for systematic lipidomics profiling, establishing a new methodological gold standard for analyzing lipid composition in vascular tissues. These contributions have provided unprecedented molecular insights into the structural and metabolic alterations driving vascular pathology. Xu’s innovative integration of advanced proteomics and lipidomics with cardiovascular research has opened new avenues for biomarker discovery and therapeutic targeting in aortic aneurysms and atherosclerosis, making him a leading figure in translational vascular biology whose methods and findings continue to guide researchers worldwide.