Kaushik Mandal

Johns Hopkins Medicine, Johns Hopkins University

Papers

Total Citations

580

H-Index

About

Kaushik Mandal is a leading researcher in cardiovascular proteomics, with a primary focus on the extracellular matrix (ECM) of the human vasculature. His seminal work includes two highly cited papers that have fundamentally advanced our understanding of vascular biology and disease. His 2010 study, "Proteomics Characterization of Extracellular Space Components in the Human Aorta" (290 citations), provided the first comprehensive map of ECM proteins in the aortic wall, establishing a critical baseline for vascular health. Building on this, his 2011 paper, "Extracellular Matrix Composition and Remodeling in Human Abdominal Aortic Aneurysms: A Proteomics Approach" (286 citations), revealed the complex ECM remodeling beyond simple elastolysis and collagenolysis that characterizes abdominal aortic aneurysms (AAA). These contributions have been instrumental in shifting the field toward a systems-level view of ECM dynamics in aneurysm pathogenesis. Beyond his proteomics work, Mandal has also demonstrated clinical versatility, as evidenced by his 2016 paper on robot-assisted cardiac surgery. With over 580 citations across his key works, his research continues to inform both basic vascular biology and translational approaches to aortic disease.