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About

Kristin C. Gunsalus is a leading figure in structural genomics and microfluidics, whose work bridges high-throughput protein production and precision biology. She is best known for her pivotal role in the Northeast Structural Genomics Consortium, where she co-authored the landmark 2005 paper "Robotic Cloning and Protein Production Platform," which has garnered over 130 citations. This work established a scalable, automated pipeline for cloning and protein expression, accelerating the field of structural biology and enabling large-scale protein characterization. More recently, Gunsalus has advanced microfluidic technologies for model organisms, notably developing a microfluidic chip capable of detecting and trapping single *C. elegans* worms for automated microplate dispensing. This innovation, published in 2016, addresses a critical bottleneck in high-throughput genetic and developmental studies, allowing for precise, individual manipulation of this key model organism. Her contributions have not only streamlined protein production for structural genomics but also opened new avenues for automated, high-resolution studies of animal development and behavior. Gunsalus’s work exemplifies the power of engineering and automation to solve fundamental biological challenges.