G.V.T. Swapna
Papers
2
Total Citations
223
H-Index
2
About
G.V.T. Swapna is a structural biologist whose work has significantly advanced our understanding of viral pathogenesis and high-throughput protein production. Her research focuses on the structural and functional characterization of viral proteins, particularly those from influenza viruses, and on developing robust platforms for protein expression. A major contribution is her role in the Northeast Structural Genomics Consortium, where she co-developed a pioneering robotic cloning and protein production platform. This system, detailed in a highly cited 2005 paper (130 citations), dramatically accelerated the pipeline for structural genomics, enabling large-scale protein production for downstream analysis. Swapna’s most impactful work, however, targets the influenza A virus. Her 2007 study (93 citations) elucidated the conserved surface features of the NS1 protein’s double-stranded RNA binding site, a critical component in the virus’s ability to counter host antiviral defenses. By mapping these structural details, her research provides a molecular blueprint for developing novel antiviral therapeutics against this deadly pathogen. Her contributions remain foundational for both structural genomics methodology and the fight against influenza.
Research Focus
Key Achievements
Top Papers
- 1
- 2