Javed Khan
Papers
1
Total Citations
93
H-Index
1
About
Javed Khan is a structural virologist whose work has illuminated how influenza viruses evade the human immune system. His research centers on the molecular architecture of viral proteins, particularly the non-structural protein 1 (NS1) from influenza A and B viruses. In his landmark 2007 study, cited over 90 times, Khan and his team revealed that conserved surface features on the NS1 protein form the critical double-stranded RNA binding site. This discovery was pivotal: it demonstrated exactly how the virus’s NS1 protein intercepts host antiviral signals, effectively disarming the cell’s first line of defense. By mapping these conserved structural motifs, Khan provided a molecular blueprint that explains a key mechanism of influenza virulence. His work has direct implications for antiviral drug design, as targeting these conserved surfaces could potentially disable multiple influenza strains. Through precise structural analysis, Javed Khan has given researchers a clear target in the ongoing battle against a virus responsible for deadly global epidemics.
Research Focus
Key Achievements
Top Papers
- 1