Cuifeng Yin
Papers
1
Total Citations
93
H-Index
1
About
Cuifeng Yin’s research has fundamentally advanced our understanding of how influenza viruses evade the host immune system. Her work centers on the structural biology of viral proteins, particularly the non-structural protein 1 (NS1) from influenza A and B viruses. In her highly cited 2007 study (93 citations), Yin and her colleagues identified conserved surface features that form the double-stranded RNA binding site of NS1, a critical domain that enables the virus to counter host antiviral defenses. This discovery provided a molecular blueprint for how NS1A, a key virulence factor, recognizes and binds double-stranded RNA, a hallmark of viral infection. By mapping these conserved structural elements, Yin’s research laid essential groundwork for understanding influenza pathogenesis and for designing targeted antiviral therapies. Her contributions have been instrumental in revealing the intricate mechanisms by which influenza viruses subvert cellular immunity, offering potential targets for therapeutic intervention against a pathogen responsible for devastating global epidemics.
Research Focus
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Top Papers
- 1