Liang Tong
Papers
1
Total Citations
93
H-Index
1
About
Liang Tong is a structural biologist renowned for his groundbreaking work on viral proteins and enzyme mechanisms. His research primarily focuses on understanding the molecular architecture of proteins involved in influenza virus pathogenesis and cellular metabolism. A landmark contribution is his elucidation of the double-stranded RNA binding site of the influenza A and B virus NS1 protein, a key virulence factor that counters host antiviral defenses. His 2007 study on this topic, cited over 90 times, revealed conserved surface features critical for RNA binding, providing a structural basis for designing antiviral therapeutics. Beyond virology, Tong has made significant advances in structural enzymology, particularly in the study of fatty acid biosynthesis and metabolic regulation. His work has been widely recognized, with several papers accumulating hundreds of citations, reflecting his impact on both basic science and translational research. Through high-resolution X-ray crystallography, Tong continues to uncover fundamental principles of protein function, offering insights that bridge molecular structure and disease intervention.
Research Focus
Key Achievements
Top Papers
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