Clemens Schulze‐Briese

Paul Scherrer Institute

Papers

4

Total Citations

182

H-Index

4

About

Clemens Schulze‐Briese is a leading figure in macromolecular crystallography, renowned for his transformative contributions to beamline instrumentation and automation at the Swiss Light Source (SLS). His research centers on developing high-precision, automated platforms that dramatically accelerate and enhance X-ray diffraction experiments for structural biology. Schulze‐Briese spearheaded the design of the SLS Crystallization Platform at Beamline X06DA, a fully automated pipeline for *in situ* screening that has garnered 94 citations for its impact on both academic and industrial workflows. He also pioneered the Parallel Robotics Inspired Goniometer (PRIGo), a compact multi-axis device (59 citations) enabling rapid, flexible sample reorientation, and the D3 diffractometer (23 citations), a cutting-edge instrument for microcrystallography that critically advanced previous undulator beamline designs. Complementing these hardware innovations, he developed automatic loop-centring algorithms to streamline data collection. Collectively, his work has established new standards for efficiency and precision in synchrotron-based crystallography, making high-throughput structural determination accessible to a broad scientific community. Schulze‐Briese’s achievements reflect a career dedicated to pushing the boundaries of experimental methodology, directly enabling breakthroughs in understanding biological macromolecules.

Research Focus

Key Achievements

4
H-Index
4
Papers
182
Total Citations
46
Avg Citations/Paper
🏆 Most Cited Paper
SLS Crystallization Platform at Beamline X06DA—A Fully Automated Pipeline Enabling <i>in Situ</i> X-ray Diffraction Screening
94 citations · 2011
📈 Most Prolific Year: 2011 (2 Papers)
🤝 Key Collaborators: 32
🏛 Institutions: Paul Scherrer Institute

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
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