Om Kumar Shrestha
Papers
1
Total Citations
17
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1
About
Om Kumar Shrestha is a pioneering researcher at the intersection of microfluidics and structural biology, whose work has fundamentally advanced high-throughput crystallographic screening. His primary contributions center on developing innovative microfluidic platforms that dramatically accelerate the process of small-molecule compound screening for protein crystallography. In his landmark 2021 study, which has garnered 17 citations, Shrestha introduced a novel capillary-based microfluidic device that enables primary high-throughput room-temperature crystallographic screening using protein crystals. This ultra-thin device, fabricated from a UV-curable polymer and patterned via cleanroom photolithography, overcomes critical bottlenecks in traditional crystallographic methods by allowing rapid, room-temperature data collection without the need for cryogenic conditions. His work represents a significant leap forward in structural biology, offering researchers a more efficient and accessible pathway to study protein-ligand interactions. Shrestha’s innovative approach has positioned him as a key figure in the development of next-generation microfluidic tools for structural biology, with his device poised to accelerate drug discovery and fundamental biological research.
Research Focus
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