A. M. Mulichak
Papers
1
Total Citations
17
H-Index
1
About
A. M. Mulichak is a structural biologist whose work bridges cutting-edge microfluidics and macromolecular crystallography to transform drug discovery. Her primary research focuses on developing high-throughput platforms for room-temperature X-ray crystallographic screening of protein–small molecule interactions. Mulichak’s most cited contribution, a 2021 study introducing a capillary-based microfluidic device, represents a paradigm shift in compound screening: by embedding protein crystals in ultra-thin, UV-curable polymer devices fabricated via cleanroom photolithography, her team enables rapid, primary screening without cryogenic cooling. This innovation directly addresses a critical bottleneck in structural biology—the time and cost of traditional cryo-crystallography—while preserving physiologically relevant room-temperature dynamics. With 17 citations to date, the work has already influenced the design of next-generation screening tools. Mulichak’s achievements exemplify how engineering principles can accelerate fundamental biological discovery, making her a key figure in the integration of microfluidics with structural biology for pharmaceutical applications.
Research Focus
Key Achievements
Top Papers
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