Jonathan Selway
Papers
1
Total Citations
17
H-Index
1
About
Jonathan Selway is a pioneer in structural biology and microfluidics, whose work has redefined the speed and efficiency of drug discovery. His primary research focuses on developing innovative microfluidic platforms for high-throughput protein crystallography, directly addressing a critical bottleneck in the field: the slow, labor-intensive process of screening small-molecule compounds. His most cited work, a 2021 study on a capillary-based microfluidic device, introduces a transformative approach that enables primary high-throughput room-temperature crystallographic screening. By engineering ultra-thin devices from UV-curable polymers using cleanroom photolithography, Selway’s method dramatically accelerates the identification of protein-ligand interactions, bypassing traditional cryogenic constraints. This breakthrough, already garnering 17 citations, offers researchers a powerful tool for real-time, room-temperature analysis, preserving protein dynamics and enhancing the relevance of structural data. Selway’s contributions stand out for their practical impact, merging microfabrication precision with biological application to streamline the path from crystal to compound. His work not only advances fundamental structural biology but also holds immense promise for accelerating the development of new therapeutics, marking him as a key innovator at the intersection of engineering and life sciences.
Research Focus
Key Achievements
Top Papers
- 1