Yutaro Tsuji

Keio University, Kanagawa Academy of Science and Technology

Papers

Total Citations

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About

Yutaro Tsuji is a researcher at the intersection of nanotechnology, biophysics, and DNA computing, whose work has pioneered new methods for molecular-scale information processing and high-throughput biosensing. His most cited paper, "Logic Gate Operation by DNA Translocation through Biological Nanopores" (2016, 48 citations), introduces a groundbreaking approach to performing logical operations using DNA molecules translocating through nanopores. This work addresses key challenges in DNA computing—namely, label-free detection and rapid operation—by leveraging nanopore technology to read out logic gate outputs in real time. Tsuji’s contributions here offer a scalable platform for programmable molecular diagnostics and synthetic biology. Earlier, he developed the "Easy and stable lipid bilayer formation: A droplets-contacting-method in parylene micropores for multiple ion channel recordings" (2011), which enabled simultaneous 16-channel recordings of ion channels through reconstituted bilayer lipid membranes. This innovation facilitates high-throughput screening (HTS) for drug discovery, a critical need in pharmaceutical research. Though less cited, this work demonstrates Tsuji’s commitment to practical, robust experimental platforms. Together, his research bridges fundamental molecular logic with applied bioengineering, making him a notable figure in nanopore-based molecular computing and biosensing.