Masahiro Takinoue
Tokyo Institute of Technology, Shanghai Institute for Science of Science
Papers
10
Total Citations
274
H-Index
6
About
Masahiro Takinoue is a pioneering researcher at the intersection of DNA nanotechnology, synthetic biology, and molecular computing, whose work has advanced our understanding of programmable biomolecular systems and artificial cell engineering. His most influential contribution—computational DNA droplets capable of recognizing microRNA inputs through liquid-liquid phase separation (2022, 82 citations)—exemplifies his innovative approach to building intelligent, self-assembling molecular systems inspired by cellular biology. Takinoue has made substantial strides in artificial cell construction, developing microfluidics-based platforms, DNA origami nanopore-functionalized emulsions, and temporally controlled droplet division systems that mimic fundamental life-like behaviors. His work on DNA logic gates using nanopore translocation (2016, 48 citations) demonstrates his ability to bridge molecular computation with label-free detection strategies. Further contributions include photolithographic shape control of DNA hydrogels and intercellular communication models using cascaded DNA reactions. Collectively, his research lays a robust foundation for molecular robotics, programmable diagnostics, and bottom-up synthetic biology. With a growing citation record spanning multiple high-impact studies, Takinoue stands as a leading voice in designing the next generation of dynamic, DNA-based artificial cellular systems.
Research Focus
Key Achievements
Top Papers
- 1
- 2Logic Gate Operation by DNA Translocation through Biological Nanopores48 citations · 2016
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- 5
- 6DNA Origami Nanoplate‐Based Emulsion with Nanopore Function28 citations · 2019
- 7DNA Origami Nanoplate‐Based Emulsion with Nanopore Function4 citations · 2019
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- 9
- 10Self-Propelled Particles with Rotationally Asymmetric Shape2 citations · 2015