Toshihisa Osaki

Kanagawa Institute of Technology, The University of Tokyo

Papers

Total Citations

125

H-Index

About

Toshihisa Osaki is a leading researcher in biohybrid nanosensors and biomimetic membrane systems, with a focus on integrating biological components into artificial devices for chemical sensing and molecular computing. His major contributions include the development of a biohybrid odorant sensor that embeds mosquito olfactory receptors (ORs) into a bilayer lipid membrane on a chip, achieving sensitive detection of the volatile compound octenol—a breakthrough with 72 citations that bridges biology and electronics for environmental and medical diagnostics. Osaki also pioneered the use of biological nanopores for DNA translocation to perform logic gate operations, enabling label-free, rapid molecular computing as demonstrated in his 2016 work (48 citations). His recent work on real-time quantitative characterization of ion channel activities (2023) advances automated control of lipid bilayer systems, enhancing reproducibility in single-molecule studies. With a career marked by interdisciplinary innovation, Osaki’s research has significant impact in bioelectronics, synthetic biology, and point-of-care sensing, making him a key figure in the development of next-generation biohybrid devices.