Papers
2
Total Citations
201
H-Index
2
About
Nobuo Misawa is a pioneer in biohybrid sensing, merging biology with microelectronics to create revolutionary odorant detection technologies. His core research focuses on biomimetic sensors, olfactory receptor engineering, and lab-on-a-chip devices. Misawa’s most celebrated contribution is the development of highly sensitive and selective odorant sensors that harness living cells—specifically *Xenopus laevis* oocytes—expressing insect olfactory receptors. His landmark 2010 paper (129 citations) demonstrated a portable fluidic device capable of detecting chemicals at concentrations as low as a few parts per billion while distinguishing between different odorants simultaneously. Building on this, his 2019 work (72 citations) achieved a breakthrough by embedding mosquito olfactory receptors into a bilayer lipid membrane on a chip, creating a stable, electrode-integrated sensor that successfully detected the volatile compound octenol. These innovations bridge the gap between biological sensitivity and electronic readout, offering transformative potential for environmental monitoring, medical diagnostics, and food safety. Misawa’s work stands as a testament to how nature’s molecular machinery can be harnessed for cutting-edge artificial sensing systems.
Research Focus
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