Yoshihiro Agari
Papers
1
Total Citations
29
H-Index
1
About
Yoshihiro Agari is a leading figure in structural genomics, with a primary focus on the thermophilic bacterium *Thermus thermophilus* HB8. His most impactful work centers on the development and application of high-throughput crystallization technologies, which have been instrumental in advancing the whole-cell structural project for this model organism. Agari’s major contribution lies in the systematic screening and optimization of protein crystallization conditions, a critical bottleneck in structural biology. His landmark 2008 paper, which has garnered 29 citations, details the integration of three conventional robotic systems—the HTS-80, Crystal Finder, and TERA—to efficiently crystallize a large number of proteins. This work established a robust pipeline for the structural genomics of *T. thermophilus* HB8, enabling the determination of numerous protein structures. By solving this technical challenge, Agari has provided a foundational resource for understanding thermostable proteins and their potential biotechnological applications, making his research a cornerstone for students and researchers in structural biology and protein engineering.
Research Focus
Key Achievements
Top Papers
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