Hitoshi Iino
Papers
1
Total Citations
29
H-Index
1
About
Hitoshi Iino is a structural biologist whose work has significantly advanced the field of structural genomics, particularly through his pioneering efforts with the thermophilic bacterium *Thermus thermophilus* HB8. His primary research focuses on high-throughput protein crystallization and the development of automated screening technologies to solve protein structures efficiently. Iino’s major contribution lies in the integration of robotic systems for crystallization, as demonstrated in his highly cited 2008 study, which introduced a comprehensive screening test using three distinct robots—the HTS-80, Crystal Finder, and TERA—to optimize both sitting-drop, hanging-drop, and microbatch vapor diffusion methods. This work, with 29 citations, was instrumental in enabling the large-scale structural determination of proteins from *T. thermophilus*, a model organism for understanding thermostability and evolution. By streamlining the crystallization pipeline, Iino’s innovations have accelerated the discovery of novel protein folds and functions, impacting fields from enzymology to drug design. His achievements underscore a legacy of merging robotics with structural biology, making him a key figure in the push toward automated, high-efficiency protein characterization.
Research Focus
Key Achievements
Top Papers
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