Yohann Misquitta
Papers
1
Total Citations
26
H-Index
1
About
Yohann Misquitta is a leading figure in structural biology, renowned for pioneering high-throughput methodologies for membrane protein crystallization. His primary research focuses on the development of automated systems to overcome the formidable challenges of working with membrane proteins, which are critical for drug discovery but notoriously difficult to crystallize. Misquitta’s most cited work, "High-Throughput Automated System for Crystallizing Membrane Proteins in Lipidic Mesophases" (2007, 26 citations), introduced a robotic platform capable of handling nanoliter volumes of highly viscous biomaterials. This innovation dramatically streamlined the *in meso* crystallization method, enabling the efficient production of crystal structures for previously intractable targets. By automating a process that was once labor-intensive and error-prone, Misquitta’s contributions have accelerated structural studies of G protein-coupled receptors and other membrane proteins, directly impacting the development of new therapeutics. His work remains a cornerstone for researchers seeking to bridge the gap between high-throughput screening and structural determination of complex biomolecules.
Research Focus
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Top Papers
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