Soon Thye Lim
Papers
1
Total Citations
64
H-Index
1
About
Dr. Soon Thye Lim is a leading hematologist-oncologist whose research centers on the molecular mechanisms and targeted therapies for B-cell lymphomas. His most impactful work, "Targeting N-myristoylation for therapy of B-cell lymphomas" (2020, 64 citations), systematically investigates N-myristoyltransferase (NMT) as a novel anti-cancer target. This seminal study demonstrates that cancer cells exhibit increased NMT expression, making this post-translational modification—critical for membrane targeting and cell signaling—a promising therapeutic vulnerability. By elucidating how N-myristoylation drives lymphoma pathogenesis, Dr. Lim has opened new avenues for drug development in hematologic malignancies. His work bridges fundamental cell biology with clinical translation, offering hope for patients with refractory B-cell lymphomas. With a growing citation impact that underscores the field's recognition of his contributions, Dr. Lim continues to shape precision oncology approaches. His research not only advances our understanding of protein lipidation in cancer but also provides a roadmap for developing NMT inhibitors as next-generation therapies, positioning him as a key figure in the fight against lymphoid cancers.
Research Focus
Key Achievements
Top Papers
- 1Targeting N-myristoylation for therapy of B-cell lymphomas64 citations · 2020