Soo‐Yong Tan
Papers
1
Total Citations
64
H-Index
1
About
Dr. Soo-Yong Tan is a leading translational researcher whose work bridges the molecular underpinnings of cancer with novel therapeutic strategies. His primary research areas focus on protein lipidation, particularly N-myristoylation, and its role in hematologic malignancies. Dr. Tan’s most impactful contribution is his seminal 2020 study, “Targeting N-myristoylation for therapy of B-cell lymphomas,” which has garnered 64 citations. In this work, he systematically investigated N-myristoyltransferase (NMT) as a druggable vulnerability in B-cell lymphomas, demonstrating that cancer cells’ reliance on increased NMT expression makes them susceptible to targeted inhibition. This research provided a compelling preclinical rationale for developing NMT inhibitors as a new class of anti-lymphoma agents. By elucidating how blocking this critical fatty acid modification disrupts membrane targeting and oncogenic signaling, Dr. Tan has opened a promising new avenue for therapy in aggressive B-cell malignancies. His work is widely recognized for its potential to translate fundamental insights into protein lipidation into tangible clinical benefits for patients.
Research Focus
Key Achievements
Top Papers
- 1Targeting N-myristoylation for therapy of B-cell lymphomas64 citations · 2020