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About

Saskia Lippens is a leading figure in the advancement of three-dimensional electron microscopy (3D EM) for the biological sciences. Her research focuses on pushing the boundaries of volume electron microscopy to visualize the complex architecture of cells and tissues at nanoscale resolution. Her most cited work, “Developing 3D SEM in a broad biological context” (2015, 107 citations), is a seminal review that helped democratize the technique by outlining practical workflows for applying serial block-face scanning electron microscopy (SBF-SEM) and focused ion beam SEM (FIB-SEM) to diverse biological questions. This contribution has been instrumental in transforming EM from a tool for 2D snapshots into a powerful method for reconstructing entire cellular landscapes. Beyond this, Lippens is recognized for her expertise in correlative light and electron microscopy (CLEM), bridging the gap between dynamic live-cell imaging and ultrastructural context. Her work, often performed at the VIB-UGent Center for Inflammation Research, has provided critical insights into cell biology, immunology, and neurobiology, making her a key enabler for researchers worldwide seeking to explore the hidden three-dimensional world within cells.