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About

Conor Mc Guire is a leading figure in the advancement of volume electron microscopy, whose work has fundamentally reshaped how biologists visualize the intricate three-dimensional architecture of cells and tissues. His primary research focuses on developing and applying novel 3D scanning electron microscopy (SEM) techniques to solve fundamental biological questions. Mc Guire’s major contribution lies in democratizing these powerful imaging methods; his seminal 2015 paper, "Developing 3D SEM in a broad biological context," which has garnered over 100 citations, serves as a critical roadmap for researchers seeking to integrate these tools into their own work. By providing clear protocols and demonstrating the broad applicability of 3D SEM—from neurobiology to cell biology—he has enabled scientists to move beyond traditional 2D snapshots and explore the true spatial relationships within cells. This work has been instrumental in revealing the complex organization of organelles and cellular networks, establishing Mc Guire as a key innovator at the intersection of method development and biological discovery.