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Miki Kojima is a leading figure in functional genomics, best known for pioneering work on transcription initiation and gene expression regulation. Her research centers on the development and application of Cap Analysis of Gene Expression (CAGE) technology, particularly for mapping transcription start sites (TSSs) at single-base resolution. Kojima’s most impactful contribution is her central role in the FANTOM5 project, where she co-authored the landmark 2017 paper detailing CAGE profiles across thousands of human and mouse samples. This work, cited over 360 times, provided an unprecedented, genome-wide atlas of promoter usage and enhancer activity, revolutionizing our understanding of transcriptional networks. She also advanced the field methodologically by developing an automated workflow for CAGE library preparation on single-molecule sequencers, a 2012 paper that has garnered 27 citations for enabling high-throughput, reproducible analysis. Kojima’s contributions have been instrumental in making CAGE a standard tool for studying gene regulation, and her work continues to empower researchers exploring the complexity of transcriptomes in health and disease.