Michel Pirocchi
Papers
2
Total Citations
99
H-Index
2
About
Michel Pirocchi is a structural biologist whose research has made significant contributions to the field of protein crystallography, particularly in advancing automation and integration within the discipline. His work focuses on streamlining the complex workflows associated with determining protein structures, with a strong emphasis on making crystallographic techniques more accessible and efficient for drug discovery applications. Pirocchi's most influential contribution, "In-plate protein crystallization, in situ ligand soaking and X-ray diffraction" (2011, 78 citations), addressed a critical bottleneck in fragment-based drug design by developing methods that allow protein crystals to be handled and analyzed directly within crystallization plates. This innovation significantly reduces the tedious manual handling traditionally required, opening the door to greater automation in ligand screening pipelines. His earlier work, "A new highly integrated sample environment for protein crystallography" (2004, 21 citations), further demonstrated his commitment to bridging gaps between sample preparation and structure determination through integrated instrumentation solutions. Together, these contributions reflect Pirocchi's enduring focus on making protein crystallography more practical and scalable, helping to accelerate the pace of structure-based drug discovery. His work remains valuable reading for researchers seeking to modernize crystallographic workflows in both academic and pharmaceutical settings.
Research Focus
Key Achievements
Top Papers
- 1
- 2A new highly integrated sample environment for protein crystallography21 citations · 2004