Shiro Fukuda
Papers
1
Total Citations
361
H-Index
1
About
Shiro Fukuda is a leading figure in functional genomics and transcriptome analysis, best known for his pivotal contributions to the FANTOM5 consortium. His most-cited work, the landmark 2017 paper on FANTOM5 CAGE profiles, has garnered over 360 citations and revolutionized our understanding of transcription initiation. In this study, Fukuda and his team mapped transcription start sites across thousands of human and mouse samples at single base-pair resolution, using Cap Analysis of Gene Expression (CAGE) coupled with single-molecule sequencing. This massive effort provided an unprecedented, high-resolution atlas of promoter and enhancer activity, enabling researchers to decode the regulatory logic of gene expression across diverse cell types and conditions. Fukuda’s work has been instrumental in advancing the fields of transcriptional regulation and systems biology, offering a foundational resource for studying development, disease, and cellular identity. His meticulous approach to large-scale data generation and analysis continues to empower scientists worldwide, making his research indispensable for anyone exploring the dynamic landscape of the transcriptome.
Research Focus
Key Achievements
Top Papers
- 1FANTOM5 CAGE profiles of human and mouse samples361 citations · 2017