Sean Brigandi

About

Sean Brigandi is a pioneering researcher in the emerging field of microbiorobotics, with a primary focus on the bioengineering and control of single-celled organisms for microscale manipulation. His most influential work centers on *Tetrahymena pyriformis*, a protozoan, which he transformed into a functional "microrobot" through artificial magnetotaxis. His landmark 2011 paper (22 citations) introduced a novel real-time feedback control system using a rapidly-exploring random tree (RRT) algorithm to guide these biohybrid agents along feasible paths—a significant step toward practical, autonomous micro-robotic systems. Brigandi’s contributions extend to characterizing the deciliation-regeneration process in *Tetrahymena* for cellular robot fabrication, and he also explored accessible robotics platforms, demonstrating the potential of LEGO Mindstorms NXT for multi-robot systems in a 2010 study (9 citations). By merging biological principles with control theory, Brigandi has laid foundational work for targeted drug delivery and microscale assembly, establishing himself as a key innovator in the intersection of biology and robotics.

Research Focus

Key Achievements

Top Papers

1. 1
   Real-time feedback control using artificial magnetotaxis with rapidly-exploring random tree (RRT) for Tetrahymena pyriformis as a microbiorobot

   22 citations · 2011
2. 2
   A LEGO Mindstorms NXT based multirobot system

   9 citations · 2010
3. 3
   Characterization of deciliation-regeneration process of Tetrahymena Pyriformis for cellular robot fabrication

   5 citations · 2011
4. 4
   Control of Tetrahymena pyriformis as a Microrobot

   4 citations · 2012

Key Collaborators

Contact & Links