N.C. Gassner
Papers
1
Total Citations
57
H-Index
1
About
N.C. Gassner is a pioneering chemical biologist whose work bridges the gap between high-throughput screening and eukaryotic cell biology. Her key research areas include bioactive small molecule discovery, yeast-based assay development, and the mechanistic study of cellular toxicity. Gassner’s major contribution is the development of a novel, automated high-throughput yeast halo assay using *Saccharomyces cerevisiae*, which dramatically accelerates the identification of biologically active compounds. This innovative platform, detailed in her most-cited 2007 paper (57 citations), enables researchers to rapidly screen for molecules that disrupt fundamental eukaryotic processes, offering a powerful tool for drug discovery and basic cell biology. The assay’s simplicity and compatibility with automation have made it a valuable resource for laboratories seeking to uncover new chemical probes. Gassner’s work exemplifies how model organisms can be leveraged for translational research, and her method continues to influence the design of yeast-based screens. Her achievements highlight a commitment to developing accessible, scalable technologies that empower the broader scientific community to explore the chemical biology of living systems.
Research Focus
Key Achievements
Top Papers
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